Farp1 - FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) Gene

Also Known as Cdep

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223254

Summary

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including dendrite morphogenesis; retrograde trans-synaptic signaling by trans-synaptic protein complex; and synapse organization. Predicted to be located in cytosol and dendrite. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in lung epithelium; nephron; nervous system; and retina. Orthologous to human FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Farp1 Products (1)

mRNA Protein Name
NM_134082.3 NP_598843.3 FERM, ARHGEF and pleckstrin domain-containing protein 1
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IGI
IGI: Inferred from genetic interaction
35676269 MGI
Biological Process GO Annotation Evidence References Source
involved in Rac protein signal transduction IGI
IGI: Inferred from genetic interaction
35676269 MGI
involved in enzyme-linked receptor protein signaling pathway IGI
IGI: Inferred from genetic interaction
14622576 MGI
involved in positive regulation of skeletal muscle acetylcholine-gated channel clustering IGI
IGI: Inferred from genetic interaction
14622576 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

FERM, ARHGEF and pleckstrin domain-containing protein 1

  • FERM, RhoGEF and pleckstrin domain-containing protein 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Farp1 NCBI NCBI:10160