Vil1 - villin 1 Gene

Also Known as Vil

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22349

Summary

Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; intestinal D-glucose absorption; and regulation of plasma membrane bounded cell projection organization. Located in several cellular components, including brush border; filopodium tip; and lamellipodium. Is expressed in several structures, including brain; egg cylinder; gut; metanephros; and reproductive system. Orthologous to human VIL1 (villin 1). [provided by Alliance of Genome Resources, Apr 2022]

Vil1 Products (1)

mRNA Protein Name
NM_009509.2 NP_033535.2 villin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
18198174 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12937273 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to hepatocyte growth factor stimulus IDA
IDA: Inferred from direct assay
12937273 MGI
involved in intestinal D-glucose absorption IGI
IGI: Inferred from genetic interaction
22114352 MGI
NOT involved in microvillus assembly IGI
IGI: Inferred from genetic interaction
22114352 MGI
involved in positive regulation of multicellular organism growth IGI
IGI: Inferred from genetic interaction
22114352 MGI
involved in positive regulation of protein localization to plasma membrane IGI
IGI: Inferred from genetic interaction
22114352 MGI
involved in regulation of lamellipodium morphogenesis IDA
IDA: Inferred from direct assay
12937273 MGI
involved in regulation of microvillus length IGI
IGI: Inferred from genetic interaction
22114352 MGI
involved in regulation of wound healing IDA
IDA: Inferred from direct assay
12937273 MGI
involved in terminal web assembly IGI
IGI: Inferred from genetic interaction
22114352 MGI
Cellular Component GO Annotation Evidence References Source
located in brush border IDA
IDA: Inferred from direct assay
22114352 MGI
located in filopodium IDA
IDA: Inferred from direct assay
16008578 MGI
located in filopodium tip IDA
IDA: Inferred from direct assay
16008578 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
12937273 MGI
located in microvillus IDA
IDA: Inferred from direct assay
21606356 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

villin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15650 VIL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vil1 NCBI NCBI:7429