Impg2 - interphotoreceptor matrix proteoglycan 2 Gene

Also Known as Rsbp; IPM200; PG10.2; Spacrcan

Species: Mus musculus

Gene Type: protein coding
Gene ID: 224224

Summary

Enables heparin binding activity and hyaluronic acid binding activity. Acts upstream of or within extracellular matrix organization; protein localization; and retina morphogenesis in camera-type eye. Located in interphotoreceptor matrix. Is expressed in embryo; retina inner nuclear layer; retina nuclear layer; and retina outer nuclear layer. Used to study retinitis pigmentosa 56 and vitelliform macular dystrophy. Human ortholog(s) of this gene implicated in retinitis pigmentosa 56 and vitelliform macular dystrophy. Orthologous to human IMPG2 (interphotoreceptor matrix proteoglycan 2). [provided by Alliance of Genome Resources, Apr 2022]

Impg2 Products (1)

mRNA Protein Name
NM_174876.3 NP_777365.2 interphotoreceptor matrix proteoglycan 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heparin binding IDA
IDA: Inferred from direct assay
15044457 MGI
enables hyaluronic acid binding IDA
IDA: Inferred from direct assay
15044457 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
32265257 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
32265257 MGI
acts upstream of or within retina morphogenesis in camera-type eye IMP
IMP: Inferred from mutant phenotype
32265257 MGI
Cellular Component GO Annotation Evidence References Source
located in interphotoreceptor matrix IDA
IDA: Inferred from direct assay
32265257 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interphotoreceptor matrix proteoglycan 2

  • sialoprotein associated with cones and rods proteoglycan

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06801 IMPG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Impg2 NCBI NCBI:50939