Clic5 - chloride intracellular channel 5 Gene

Also Known as jbg; Gm322; nmf318; B330005L24; 5730531E12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 224796

Summary

Predicted to enable Chloride Channel activity. Acts upstream of or within several processes, including auditory receptor cell stereocilium organization; diet induced thermogenesis; and sensory perception of sound. Located in stereocilium. Is expressed in several structures, including brain; gut; inner ear; lung; and metanephros. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 103. Orthologous to human CLIC5 (chloride intracellular channel 5). [provided by Alliance of Genome Resources, Apr 2022]

Clic5 Products (1)

mRNA Protein Name
NM_172621.2 NP_766209.1 chloride intracellular channel protein 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24285636 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within auditory receptor cell stereocilium organization IMP
IMP: Inferred from mutant phenotype
17021174 MGI
acts upstream of or within diet induced thermogenesis IMP
IMP: Inferred from mutant phenotype
20357015 MGI
involved in inner ear receptor cell stereocilium organization IMP
IMP: Inferred from mutant phenotype
24285636 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: Inferred from mutant phenotype
17021174 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
17021174 MGI
involved in protein localization IMP
IMP: Inferred from mutant phenotype
24285636 MGI
acts upstream of or within response to dietary excess IMP
IMP: Inferred from mutant phenotype
20357015 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
17021174 MGI
Cellular Component GO Annotation Evidence References Source
located in stereocilium IDA
IDA: Inferred from direct assay
17021174 MGI
located in stereocilium base IDA
IDA: Inferred from direct assay
37952086 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chloride intracellular channel protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02807 CLIC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20382 Clic5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26892 Clic5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clic5 NCBI NCBI:53405