2. Gene
  3. Prdm6 - PR domain containing 6 Gene

Prdm6 - PR domain containing 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm92; PRISM

Gene ID: 225518 | Gene type: protein coding

About Prdm6

Summary

Enables identical protein binding activity. Acts upstream of or within negative regulation of smooth muscle cell differentiation; negative regulation of transcription, DNA-templated; and neurogenesis. Located in nucleus. Is expressed in several structures, including arterial system; central nervous system; genitourinary system; heart; and respiratory system. Human ortholog(s) of this gene implicated in patent ductus arteriosus. Orthologous to human PRDM6 (PR/SET domain 6). [provided by Alliance of Genome Resources, Apr 2022]

Prdm6 Products(1)

mRNA Protein Name
NM_001033281.3 NP_001028453.1 putative histone-lysine N-methyltransferase PRDM6
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
16537907 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
16537907 MGI
acts upstream of or within negative regulation of smooth muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
16537907 MGI
acts upstream of or within neurogenesis IDA
IDA: Inferred from direct assay
19050759 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
16537907 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

putative histone-lysine N-methyltransferase PRDM6

PR domain-containing protein 6

PR domain-containing protein in smooth muscle

PR-domain zinc finger protein 6

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11070 PRDM6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdm6 NCBI NCBI:93166