Trpm6 - transient receptor potential cation channel, subfamily M, member 6 Gene

Also Known as CHAK2; TRPM6/CHAK2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 225997

Summary

Enables cation channel activity. Acts upstream of or within metal ion transport. Located in apical plasma membrane and brush border membrane. Is expressed in several structures, including cochlea; colon; extraembryonic component; ganglia; and genitourinary system. Human ortholog(s) of this gene implicated in intestinal hypomagnesemia 1 and metal metabolism disorder. Orthologous to human TRPM6 (transient receptor potential cation channel subfamily M member 6). [provided by Alliance of Genome Resources, Apr 2022]

Trpm6 Products (1)

mRNA Protein Name
NM_153417.2 NP_700466.1 transient receptor potential cation channel subfamily M member 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
14576148 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within metal ion transport IDA
IDA: Inferred from direct assay
14576148 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
14576148 MGI
located in brush border membrane IDA
IDA: Inferred from direct assay
14576148 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transient receptor potential cation channel subfamily M member 6

  • melastatin-related TRP cation channel 6

  • putative cation channel subfamily M member 6

  • transient receptor potential cation channel 6/channel-kinase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103073 Mesendogen Inhibitor 99.84% Unkown
HY-RS15116 TRPM6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20503 Trpm6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27011 Trpm6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpm6 NCBI NCBI:140803