Cox15 - cytochrome c oxidase assembly protein 15 Gene

Predicted to enable molecular adaptor activity and oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme A biosynthetic process and respiratory chain complex IV assembly. Predicted to act upstream of or within proton transmembrane transport. Located in mitochondrial inner membrane. Is expressed in several structures, including adipose tissue; alimentary system; eye; genitourinary system; and nervous system. Human ortholog(s) of this gene implicated in Leigh disease; fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 2; and hypertrophic cardiomyopathy. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15). [provided by Alliance of Genome Resources, Apr 2022]