Dpcd - deleted in primary ciliary dyskinesia Gene

Also Known as Ndac; Gm17018

Species: Mus musculus

Gene Type: protein coding

Gene ID: 226162

Summary

Acts upstream of or within several processes, including flagellated sperm motility; left/right pattern formation; and ventricular system development. Used to study hydrocephalus and primary ciliary dyskinesia. Orthologous to human DPCD (deleted in primary ciliary dyskinesia homolog (mouse)). [provided by Alliance of Genome Resources, Apr 2022]

Dpcd Products (2)

mRNA	Protein	Name
NM_001356947.1	NP_001343876.1	protein DPCD isoform 2
NM_172639.3	NP_766227.1	protein DPCD isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	29959317	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within determination of left/right symmetry	IMP IMP: Inferred from mutant phenotype	21746835	MGI
acts upstream of or within epithelial cilium movement involved in extracellular fluid movement	IMP IMP: Inferred from mutant phenotype	20080492	MGI
acts upstream of or within establishment of localization in cell	IMP IMP: Inferred from mutant phenotype	21746835	MGI
acts upstream of or within flagellated sperm motility	IMP IMP: Inferred from mutant phenotype	20080492	MGI
acts upstream of or within lateral ventricle development	IMP IMP: Inferred from mutant phenotype	20080492	MGI
acts upstream of or within left/right pattern formation	IMP IMP: Inferred from mutant phenotype	20080492	MGI
acts upstream of or within spermatogenesis	IMP IMP: Inferred from mutant phenotype	21746835	MGI
acts upstream of or within third ventricle development	IMP IMP: Inferred from mutant phenotype	20080492	MGI
acts upstream of or within ventricular system development	IMP IMP: Inferred from mutant phenotype	21746835	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
protein DPCD	neighbor of Dac

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03946	DPCD Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dpcd	NCBI	NCBI:25911