Epb41l5 - erythrocyte membrane protein band 4.1 like 5 Gene

Also Known as BE37; NBL5; Lulu1; Epb4.1l5; 1700030C16Rik; E230025E14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 226352

Summary

Enables protein domain specific binding activity. Involved in epithelial to mesenchymal transition. Acts upstream of or within several processes, including chordate embryonic development; embryonic foregut morphogenesis; and mesoderm morphogenesis. Located in focal adhesion and ruffle membrane. Is expressed in several structures, including foregut; lung; metanephros; neural tube; and primitive streak. Orthologous to human EPB41L5 (erythrocyte membrane protein band 4.1 like 5). [provided by Alliance of Genome Resources, Apr 2022]

Epb41l5 Products (2)

mRNA Protein Name
NM_001113416.1 NP_001106887.1 band 4.1-like protein 5 isoform 2
NM_145506.4 NP_663481.2 band 4.1-like protein 5 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18794329 MGI
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
18794329 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin cytoskeleton organization IDA
IDA: Inferred from direct assay
17507402 MGI
acts upstream of or within actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
17507402 MGI
acts upstream of or within actomyosin structure organization IDA
IDA: Inferred from direct assay
20103536 MGI
acts upstream of or within apical constriction IDA
IDA: Inferred from direct assay
20103536 MGI
acts upstream of or within axial mesoderm development IMP
IMP: Inferred from mutant phenotype
15755804 MGI
acts upstream of or within axial mesoderm morphogenesis IMP
IMP: Inferred from mutant phenotype
17507402 MGI
acts upstream of or within cell morphogenesis IMP
IMP: Inferred from mutant phenotype
20678497 MGI
acts upstream of or within cellular response to transforming growth factor beta stimulus IDA
IDA: Inferred from direct assay
18794329 MGI
acts upstream of or within ectoderm development IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within embryonic foregut morphogenesis IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within endoderm development IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within epithelial cell morphogenesis IMP
IMP: Inferred from mutant phenotype
18794329 MGI
involved in epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
17507402 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within left/right axis specification IMP
IMP: Inferred from mutant phenotype
20678497 MGI
acts upstream of or within mesoderm development IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within mesoderm migration involved in gastrulation IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within negative regulation of cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within negative regulation of protein binding IDA
IDA: Inferred from direct assay
18794329 MGI
acts upstream of or within neural plate morphogenesis IMP
IMP: Inferred from mutant phenotype
17507402 MGI
acts upstream of or within paraxial mesoderm development IMP
IMP: Inferred from mutant phenotype
15755804 MGI
acts upstream of or within positive regulation of cell-matrix adhesion IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within positive regulation of epithelial cell migration IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within positive regulation of focal adhesion assembly IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within positive regulation of protein binding IDA
IDA: Inferred from direct assay
18794329 MGI
acts upstream of or within post-transcriptional regulation of gene expression IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within regulation of establishment of protein localization IDA
IDA: Inferred from direct assay
18794329 MGI
acts upstream of or within somite rostral/caudal axis specification IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within somitogenesis IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within substrate-dependent cell migration, cell attachment to substrate IMP
IMP: Inferred from mutant phenotype
18794329 MGI
acts upstream of or within unidimensional cell growth IDA
IDA: Inferred from direct assay
20103536 MGI
Cellular Component GO Annotation Evidence References Source
located in cell leading edge IDA
IDA: Inferred from direct assay
18794329 MGI
located in focal adhesion IDA
IDA: Inferred from direct assay
18794329 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
17920587 MGI
located in ruffle membrane IDA
IDA: Inferred from direct assay
18794329 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

band 4.1-like protein 5

  • erythrocyte protein band 4.1-like 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04416 EPB41L5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epb41l5 NCBI NCBI:57669