2. Gene
  3. EPB41L5 - erythrocyte membrane protein band 4.1 like 5 Gene

EPB41L5 - erythrocyte membrane protein band 4.1 like 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as YRT; BE37; LULU; YMO1; LULU1

Gene ID: 57669 | Gene type: protein coding

About EPB41L5

Cytogenetic location: 2q14.2 Genomic coordinates (GRCh38): 2:120,013,077-120,179,119 (from NCBI)

This gene has 10 transcripts (splice variants), 213 orthologues and 10 paralogues. Broad expression in testis (RPKM 10.7), thyroid (RPKM 7.3) and 24 other tissues.

Summary

Predicted to enable cytoskeletal protein binding activity and protein domain specific binding activity. Predicted to be involved in actomyosin structure organization. Predicted to act upstream of or within several processes, including chordate embryonic development; embryonic foregut morphogenesis; and mesoderm morphogenesis. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EPB41L5 Products(6)

mRNA Protein Name
NM_001184937.2 NP_001171866.1 band 4.1-like protein 5 isoform 2
NM_001184938.4 NP_001171867.1 band 4.1-like protein 5 isoform 3
NM_001184939.3 NP_001171868.1 band 4.1-like protein 5 isoform 3
NM_001330307.2 NP_001317236.1 band 4.1-like protein 5 isoform 4
NM_001330310.2 NP_001317239.1 band 4.1-like protein 5 isoform 5
NM_020909.4 NP_065960.2 band 4.1-like protein 5 isoform 1

EPB41L5 Protein Structure

FERM_N

FERM_N: FERM N-terminal domain (47 - 123)

FERM_M

FERM_M: FERM central domain (127 - 235)

FERM_C

FERM_C: FERM C-terminal PH-like domain (241 - 330)

FA

FA: FERM adjacent (FA) (336 - 379)

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  • 600
  • 733 a.a.
Protein Preferred Names Protein Names

band 4.1-like protein 5

yurt homolog

Related Diseases

Diseases Alias
Spinal Cord Astrocytoma

Astrocytoma Of Spinal Cord

Spinal Astrocytoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04416 EPB41L5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EPB41L5 MGD MGI:103006
Rattus norvegicus EPB41L5 RGD RGD:1311366
Macaca mulatta EPB41L5 VGNC VGNC:72072
Felis catus EPB41L5 VGNC VGNC:80194
Bos taurus EPB41L5 VGNC VGNC:28525
Canis familiaris EPB41L5 VGNC VGNC:40398