EPB41L5 - erythrocyte membrane protein band 4.1 like 5 Gene

Also Known as YRT; BE37; LULU; YMO1; LULU1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57669

About EPB41L5

Cytogenetic location: 2q14.2 Genomic coordinates (GRCh38): 2:120,013,077-120,179,119 (from NCBI)

This gene has 10 transcripts (splice variants), 213 orthologues and 10 paralogues. Broad expression in testis (RPKM 10.7), thyroid (RPKM 7.3) and 24 other tissues.

Summary

Predicted to enable cytoskeletal protein binding activity and protein domain specific binding activity. Predicted to be involved in actomyosin structure organization. Predicted to act upstream of or within several processes, including chordate embryonic development; embryonic foregut morphogenesis; and mesoderm morphogenesis. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EPB41L5 Products (6)

mRNA Protein Name
NM_001184937.2 NP_001171866.1 band 4.1-like protein 5 isoform 2
NM_001184938.4 NP_001171867.1 band 4.1-like protein 5 isoform 3
NM_001184939.3 NP_001171868.1 band 4.1-like protein 5 isoform 3
NM_001330307.2 NP_001317236.1 band 4.1-like protein 5 isoform 4
NM_001330310.2 NP_001317239.1 band 4.1-like protein 5 isoform 5
NM_020909.4 NP_065960.2 band 4.1-like protein 5 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17920587 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EPB41L5 Protein Structure

FERM_N

FERM_N: FERM N-terminal domain (47 - 123)

FERM_M

FERM_M: FERM central domain (127 - 235)

FERM_C

FERM_C: FERM C-terminal PH-like domain (241 - 330)

FA

FA: FERM adjacent (FA) (336 - 379)

  • 0
  • 200
  • 400
  • 600
  • 733 a.a.
Protein Preferred Names Protein Names

band 4.1-like protein 5

  • yurt homolog

EPB41L5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
EPB41L5 Q9HCM4 CRB3 Homo sapiens Q9BUF7
Pull Down
17920587
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spinal Cord Astrocytoma

  • Astrocytoma Of Spinal Cord

  • Spinal Astrocytoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04416 EPB41L5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EPB41L5 MGD MGI:103006
Rattus norvegicus EPB41L5 RGD RGD:1311366
Macaca mulatta EPB41L5 VGNC VGNC:72072
Felis catus EPB41L5 VGNC VGNC:80194
Bos taurus EPB41L5 VGNC VGNC:28525
Canis familiaris EPB41L5 VGNC VGNC:40398
Others EPB41L5 NCBI