Rnf112 - ring finger protein 112 Gene

Also Known as bfp; ZNF179; Zfp179; neurolastin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22671

Summary

Enables several functions, including GTP binding activity; GTPase activity; and ubiquitin protein Ligase activity. Involved in several processes, including cell death in response to hydrogen peroxide; embryonic brain development; and protein autoubiquitination. Acts upstream of or within G1 to G0 transition involved in cell differentiation; positive regulation of glial cell differentiation; and positive regulation of neuron differentiation. Located in several cellular components, including cytoplasmic vesicle; nuclear body; and postsynaptic density. Is extrinsic component of membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and respiratory system. Orthologous to human RNF112 (ring finger protein 112). [provided by Alliance of Genome Resources, Apr 2022]

Rnf112 Products (3)

mRNA Protein Name
NM_001291024.1 NP_001277953.1 RING finger protein 112 isoform 2
NM_001359130.1 NP_001346059.1 RING finger protein 112 isoform 3
NM_009548.3 NP_033574.2 RING finger protein 112 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTP binding IMP
IMP: Inferred from mutant phenotype
26212327 MGI
enables GTPase activity IDA
IDA: Inferred from direct assay
26212327 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24359566 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
26212327 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G1 to G0 transition involved in cell differentiation IMP
IMP: Inferred from mutant phenotype
21566658 MGI
involved in embryonic brain development IMP
IMP: Inferred from mutant phenotype
26951452 MGI
involved in neuron differentiation IMP
IMP: Inferred from mutant phenotype
28684796 MGI
acts upstream of or within positive regulation of glial cell differentiation IMP
IMP: Inferred from mutant phenotype
21566658 MGI
acts upstream of or within positive regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
21566658 MGI
involved in protein autoubiquitination IDA
IDA: Inferred from direct assay
26212327 MGI
involved in response to hydroperoxide IDA
IDA: Inferred from direct assay
27918959 MGI
Cellular Component GO Annotation Evidence References Source
located in cell body IDA
IDA: Inferred from direct assay
26951452 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
9806830 MGI
located in endosome IDA
IDA: Inferred from direct assay
26212327 MGI
located in nuclear body IDA
IDA: Inferred from direct assay
24359566 MGI
located in nucleoplasm IDA
IDA: Inferred from direct assay
24359566 MGI
located in nucleus IDA
IDA: Inferred from direct assay
9806830 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
26212327 MGI
located in synaptic vesicle IDA
IDA: Inferred from direct assay
26212327 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RING finger protein 112

  • brain finger protein

  • zinc finger protein 179

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12037 RNF112 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf112 NCBI NCBI:7732