2. Gene
  3. Becn2 - beclin 2 Gene

Becn2 - beclin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm104; Gm38100; Beclin-2

Gene ID: 226720 | Gene type: protein coding

About Becn2

Summary

Involved in endosome to lysosome transport. Acts upstream of or within G protein-coupled receptor catabolic process; autophagy; and glucose homeostasis. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex, class III, type I and phosphatidylinositol 3-kinase complex, class III, type II. Predicted to be active in phagophore assembly site. Is expressed in several structures, including liver; reproductive system; skeletal muscle; stomach; and thymus. Orthologous to human BECN2 (beclin 2). [provided by Alliance of Genome Resources, Apr 2022]

Becn2 Products(1)

mRNA Protein Name
NM_001290692.1 NP_001277621.1 beclin-2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23954414 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
23954414 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within G protein-coupled receptor catabolic process IMP
IMP: Inferred from mutant phenotype
23954414 MGI
involved in G protein-coupled receptor catabolic process IMP
IMP: Inferred from mutant phenotype
23954414 MGI
acts upstream of or within autophagy IMP
IMP: Inferred from mutant phenotype
23954414 MGI
involved in autophagy IMP
IMP: Inferred from mutant phenotype
23954414 MGI
involved in endosome to lysosome transport IMP
IMP: Inferred from mutant phenotype
23954414 MGI
acts upstream of or within glucose homeostasis IGI
IGI: Inferred from genetic interaction
23954414 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beclin-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01466 BECN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Becn2 NCBI NCBI:441925