Pms1 - PMS1 homolog 1, mismatch repair system component Gene

Mus musculus

Gene ID: 227099 | Gene type: protein coding

About Pms1

Summary

Predicted to enable ATP hydrolysis activity and enzyme binding activity. Acts upstream of or within mismatch repair. Predicted to be located in nucleus. Predicted to be part of mismatch repair complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and integumental system. Human ortholog(s) of this gene implicated in Lynch syndrome; dermatomyositis; pancreatic ductal carcinoma; and polymyositis. Orthologous to human PMS1 (PMS1 homolog 1, mismatch repair system component). [provided by Alliance of Genome Resources, Apr 2022]

Pms1 Products(1)

mRNA	Protein	Name
NM_153556.2	NP_705784.1	PMS1 protein homolog 1

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within mismatch repair	IMP IMP: Inferred from mutant phenotype	9500552	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

PMS1 protein homolog 1

postmeiotic segregation increased 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-D0937	Methoxy-PMS		99.32%	Unkown
HY-RS10772	PMS1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pms1	NCBI	NCBI:5378

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