Plcl1 - phospholipase C-like 1 Gene

Also Known as PLCE; PLCL; PRIP; PLC-L; PLDL1; PLC-L1; PRIP-1; C230017K02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 227120

Summary

Predicted to enable GABA Receptor binding activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including gamma-aminobutyric acid signaling pathway; regulation of GABAergic synaptic transmission; and regulation of peptidyl-serine phosphorylation. Located in plasma membrane. Is expressed in nervous system and vibrissa. Orthologous to human PLCL1 (Phospholipase C like 1 (inactive)). [provided by Alliance of Genome Resources, Apr 2022]

Plcl1 Products (1)

mRNA Protein Name
NM_001114663.1 NP_001108135.1 inactive phospholipase C-like protein 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within gamma-aminobutyric acid signaling pathway IGI
IGI: Inferred from genetic interaction
16754670 MGI
involved in negative regulation of cold-induced thermogenesis IGI
IGI: Inferred from genetic interaction
26706316 MGI
acts upstream of or within positive regulation of receptor binding IGI
IGI: Inferred from genetic interaction
16754670 MGI
acts upstream of or within regulation of synaptic transmission, GABAergic IGI
IGI: Inferred from genetic interaction
16754670 MGI
acts upstream of or within regulation of synaptic transmission, GABAergic IMP
IMP: Inferred from mutant phenotype
15464766 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inactive phospholipase C-like protein 1

  • phospholipase C, eta 2 pseudogene

  • phospholipase C-related but catalytically inactive protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10664 PLCL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plcl1 NCBI NCBI:5334