Ctdsp1 - CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 Gene

Mus musculus

Also known as GIP; Nif3; SCP1; NLIIF

Gene ID: 227292 | Gene type: protein coding

About Ctdsp1

Summary

Predicted to enable RNA polymerase II CTD heptapeptide repeat Phosphatase activity. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cell differentiation; and negative regulation of protein phosphorylation. Predicted to be located in nucleoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and integumental system. Orthologous to human CTDSP1 (CTD small Phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ctdsp1 Products(1)

mRNA	Protein	Name
NM_153088.2	NP_694728.1	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	14743429	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle	IDA IDA: Inferred from direct assay	22210897	MGI
acts upstream of or within negative regulation of neurogenesis	IDA IDA: Inferred from direct assay	17403776	MGI
acts upstream of or within negative regulation of neurogenesis	IGI IGI: Inferred from genetic interaction	17403776	MGI
acts upstream of or within negative regulation of neurogenesis	IMP IMP: Inferred from mutant phenotype	17403776	MGI
acts upstream of or within negative regulation of neuron differentiation	IDA IDA: Inferred from direct assay	17403776	MGI
acts upstream of or within negative regulation of protein phosphorylation	IDA IDA: Inferred from direct assay	22210897	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

NLI-interacting factor 3	golli-interacting protein
nuclear LIM interactor-interacting factor 3	small C-terminal domain phosphatase 1
small CTD phosphatase 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03291	CTDSP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ctdsp1	NCBI	NCBI:58190

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