Dgkd - diacylglycerol kinase, delta Gene

Mus musculus

Also known as dgkd-2; DGKdelta; D330025K09

Gene ID: 227333 | Gene type: protein coding

About Dgkd

Summary

Enables diacylglycerol kinase activity. Involved in diacylglycerol metabolic process; lipid phosphorylation; and regulation of signal transduction. Predicted to be located in clathrin-coated pit; cytoplasmic vesicle; and cytosol. Is expressed in several structures, including brain; immune system; musculature; reproductive system; and stomach. Used to study Lennox-Gastaut syndrome. Orthologous to human DGKD (diacylglycerol kinase delta). [provided by Alliance of Genome Resources, Apr 2022]

Dgkd Products(1)

mRNA	Protein	Name
NM_177646.3	NP_808314.2	diacylglycerol kinase delta

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables ATP-dependent diacylglycerol kinase activity	IMP IMP: Inferred from mutant phenotype	17021016	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in diacylglycerol catabolic process	IMP IMP: Inferred from mutant phenotype	17021016	MGI
involved in negative regulation of phospholipase C/protein kinase C signal transduction	IMP IMP: Inferred from mutant phenotype	17021016	MGI
involved in positive regulation of epidermal growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	17021016	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

diacylglycerol kinase delta

DAG kinase delta

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03717	DGKD Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dgkd	NCBI	NCBI:8527

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