2. Gene
  3. Qrfp - pyroglutamylated RFamide peptide Gene

Qrfp - pyroglutamylated RFamide peptide Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as P518

Gene ID: 227717 | Gene type: protein coding

About Qrfp

Summary

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. The encoded products are members of the RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (F). These products include the neuropeptides QRFP-26 (26RFa) and the N-terminally extended form, QRFP-43 (43RFa). Both of these neuropeptides bind to the pyroglutamylated RFamide peptide receptor (QRFPR) and may regulate blood pressure, reproduction and food intake. [provided by RefSeq, Sep 2015]

Qrfp Products(1)

mRNA Protein Name
NM_183424.4 NP_906269.1 orexigenic neuropeptide QRFP preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables orexigenic neuropeptide QRFP receptor binding IDA
IDA: Inferred from direct assay
16648250 MGI
Biological Process GO Annotation Evidence Reference Source
involved in grooming behavior IDA
IDA: Inferred from direct assay
16648250 MGI
involved in locomotory behavior IDA
IDA: Inferred from direct assay
16648250 MGI
involved in positive regulation of blood pressure IDA
IDA: Inferred from direct assay
16648250 MGI
involved in regulation of feeding behavior IDA
IDA: Inferred from direct assay
16648250 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

orexigenic neuropeptide QRFP

P518 precursor protein (P518)

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11504 QRFP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Qrfp NCBI NCBI:347148