Ano3 - anoctamin 3 Gene

Also Known as Tmem16c; B230324K02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 228432

Summary

Enables phospholipid scramblase activity. Acts upstream of or within calcium activated galactosylceramide scrambling and calcium activated phosphatidylcholine scrambling. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; apical ectodermal ridge; nervous system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in dystonia 24. Orthologous to human ANO3 (anoctamin 3). [provided by Alliance of Genome Resources, Apr 2022]

Ano3 Products (4)

mRNA Protein Name
NM_001128103.2 NP_001121575.1 anoctamin-3 isoform 1
NM_001355244.1 NP_001342173.1 anoctamin-3 isoform 2
NM_001355245.1 NP_001342174.1 anoctamin-3 isoform 3
NM_001355246.1 NP_001342175.1 anoctamin-3 isoform 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
NOT enables intracellularly calcium-gated chloride channel activity IDA
IDA: Inferred from direct assay
23532839 MGI
enables phospholipid scramblase activity IDA
IDA: Inferred from direct assay
23532839 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within calcium activated galactosylceramide scrambling IDA
IDA: Inferred from direct assay
23532839 MGI
acts upstream of or within calcium activated phosphatidylcholine scrambling IDA
IDA: Inferred from direct assay
23532839 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: Inferred from direct assay
23532839 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anoctamin-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00743 ANO3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ano3 NCBI NCBI:63982