Dlgap4 - DLG associated protein 4 Gene

Mus musculus

Also known as DAP4; DAP-4; WBP16; Sapap4; SAPAP-4

Gene ID: 228836 | Gene type: protein coding

About Dlgap4

Summary

This gene encodes a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. The encoded protein may play a role in synapse organization and neuronal signalling. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Mar 2013]

Dlgap4 Products(5)

mRNA	Protein	Name
NM_001042487.1	NP_001035952.1	disks large-associated protein 4 isoform b
NM_001042488.2	NP_001035953.1	disks large-associated protein 4 isoform c
NM_001277186.1	NP_001264115.1	disks large-associated protein 4 isoform d
NM_001277187.1	NP_001264116.1	disks large-associated protein 4 isoform e
NM_146128.6	NP_666240.4	disks large-associated protein 4 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	23055941	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in modification of postsynaptic structure	IDA IDA: Inferred from direct assay	30664629	MGI
involved in modification of postsynaptic structure	IMP IMP: Inferred from mutant phenotype	30664629	MGI
involved in regulation of synapse maturation	IDA IDA: Inferred from direct assay	30664629	MGI
involved in regulation of synapse maturation	IMP IMP: Inferred from mutant phenotype	30664629	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cholinergic synapse	IDA IDA: Inferred from direct assay	15024750	MGI
is active in cholinergic synapse	IEP IEP: Inferred from expression pattern	15024750	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	15024750	MGI
is active in glutamatergic synapse	IEP IEP: Inferred from expression pattern	15024750	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	30664629	MGI
is active in neuromuscular junction	IDA IDA: Inferred from direct assay	15024750	MGI
is active in neuromuscular junction	IEP IEP: Inferred from expression pattern	15024750	MGI
is active in postsynaptic specialization	IDA IDA: Inferred from direct assay	15024750	MGI
is active in postsynaptic specialization	IEP IEP: Inferred from expression pattern	15024750	MGI
located in synapse	IDA IDA: Inferred from direct assay	15024750	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

disks large-associated protein 4

PSD-95/SAP90-binding protein 4	SAP90/PSD-95-associated protein 4
WW domain-binding protein 16	discs, large homolog-associated protein 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03804	DLGAP4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dlgap4	NCBI	NCBI:22839

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