Tgif2 - TGFB-induced factor homeobox 2 Gene

Also Known as 4921501K24; 5730599O09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 228839

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including nodal signaling pathway; positive regulation of neuron differentiation; and regulation of gastrulation. Predicted to be located in centrosome and nucleoplasm. Is expressed in several structures, including alimentary system; brain; forelimb phalanx; genitourinary system; and sensory organ. Orthologous to several human genes including TGIF2-RAB5IF (TGIF2-RAB5IF readthrough). [provided by Alliance of Genome Resources, Apr 2022]

Tgif2 Products (2)

mRNA Protein Name
NM_001291124.1 NP_001278053.1 homeobox protein TGIF2 isoform b
NM_173396.3 NP_775572.1 homeobox protein TGIF2 isoform a

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of amacrine cell differentiation IDA
IDA: Inferred from direct assay
18926818 MGI
acts upstream of neuron differentiation IDA
IDA: Inferred from direct assay
18926818 MGI
acts upstream of or within nodal signaling pathway IGI
IGI: Inferred from genetic interaction
20040491 MGI
acts upstream of or within positive regulation of amacrine cell differentiation IDA
IDA: Inferred from direct assay
18926818 MGI
acts upstream of or within regulation of gastrulation IGI
IGI: Inferred from genetic interaction
20040491 MGI
acts upstream of or within retina development in camera-type eye IDA
IDA: Inferred from direct assay
18926818 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein TGIF2

  • 5'-TG-3'-interacting factor 2

  • TALE family homeobox

  • TGF-beta-induced transcription factor 2

  • TGFB-induced factor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14456 TGIF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14457 TGIF2LX Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tgif2 NCBI NCBI:60436