Themis2 - thymocyte selection associated family member 2 Gene

Also Known as ICB-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 230787

Summary

Involved in regulation of B cell activation. Acts upstream of or within T cell receptor signaling pathway. Located in cytoplasm and nucleus. Orthologous to human THEMIS2 (thymocyte selection associated family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Themis2 Products (1)

mRNA Protein Name
NM_001033308.2 NP_001028480.1 protein THEMIS2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22732588 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
22732588 MGI
involved in regulation of B cell activation IMP
IMP: Inferred from mutant phenotype
24907343 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22732588 MGI
located in nucleus IDA
IDA: Inferred from direct assay
22732588 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein THEMIS2

  • basement membrane-induced protein

  • induced by contact to basement membrane 1 protein

  • protein ICB-1

  • thymocyte-expressed molecule involved in selection protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14489 THEMIS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Themis2 NCBI NCBI:9473