Wdtc1 - WD and tetratricopeptide repeats 1 Gene

Mus musculus

Also known as adp; Gm695; adipose

Gene ID: 230796 | Gene type: protein coding

About Wdtc1

Summary

Enables enzyme inhibitor activity; histone binding activity; and histone deacetylase binding activity. Acts upstream of or within several processes, including cellular response to Insulin stimulus; glucose metabolic process; and negative regulation of cellular biosynthetic process. Located in cytosol and nucleus. Is expressed in heart left ventricle; heart right ventricle; left lung; pancreas; and right lung. Orthologous to human WDTC1 (WD and tetratricopeptide repeats 1). [provided by Alliance of Genome Resources, Apr 2022]

Wdtc1 Products(1)

mRNA	Protein	Name
NM_199306.4	NP_955010.1	WD and tetratricopeptide repeats protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables enzyme inhibitor activity	IDA IDA: Inferred from direct assay	17767906	MGI
enables histone binding	IDA IDA: Inferred from direct assay	17767906	MGI
enables histone binding	IPI IPI: Inferred from physical interaction	17767906	MGI
enables histone deacetylase binding	IPI IPI: Inferred from physical interaction	17767906	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular response to insulin stimulus	IMP IMP: Inferred from mutant phenotype	17767906	MGI
acts upstream of or within glucose metabolic process	IMP IMP: Inferred from mutant phenotype	17767906	MGI
acts upstream of or within in utero embryonic development	IMP IMP: Inferred from mutant phenotype	17767906	MGI
acts upstream of or within intracellular chemical homeostasis	IMP IMP: Inferred from mutant phenotype	17767906	MGI
acts upstream of or within multicellular organism growth	IMP IMP: Inferred from mutant phenotype	17767906	MGI
acts upstream of or within negative regulation of fatty acid biosynthetic process	IDA IDA: Inferred from direct assay	17767906	MGI
acts upstream of or within negative regulation of fatty acid biosynthetic process	IMP IMP: Inferred from mutant phenotype	17767906	MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	17767906	MGI
acts upstream of or within regulation of cell size	IMP IMP: Inferred from mutant phenotype	17767906	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytosol	IDA IDA: Inferred from direct assay	17767906	MGI
located in nucleus	IDA IDA: Inferred from direct assay	17767906	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

WD and tetratricopeptide repeats protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15804	WDTC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Wdtc1	NCBI	NCBI:23038

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