Eif4g3 - eukaryotic translation initiation factor 4 gamma, 3 Gene

Also Known as repro8; Gm32394; eIF4GII; G1-419-52; 1500002J22Rik; 4930523M17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 230861

Summary

Predicted to enable mRNA binding activity and translation initiation factor activity. Acts upstream of or within positive regulation of cellular protein metabolic process; positive regulation of meiosis I; and spermatogenesis. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in nervous system; neural retina; and submandibular gland primordium. Orthologous to human EIF4G3 (eukaryotic translation initiation factor 4 gamma 3). [provided by Alliance of Genome Resources, Apr 2022]

Eif4g3 Products (7)

mRNA Protein Name
NM_001256195.1 NP_001243124.1 eukaryotic translation initiation factor 4 gamma 3 isoform 2
NM_001256198.1 NP_001243127.1 eukaryotic translation initiation factor 4 gamma 3 isoform 3
NM_001355699.1 NP_001342628.1 eukaryotic translation initiation factor 4 gamma 3 isoform 4
NM_001355700.1 NP_001342629.1 eukaryotic translation initiation factor 4 gamma 3 isoform 5
NM_001369130.1 NP_001356059.1 eukaryotic translation initiation factor 4 gamma 3 isoform 6
NM_001369131.1 NP_001356060.1 eukaryotic translation initiation factor 4 gamma 3 isoform 7
NM_172703.3 NP_766291.2 eukaryotic translation initiation factor 4 gamma 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19114715 MGI
enables translation initiation factor activity IDA
IDA: Inferred from direct assay
35951695 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of meiosis I IMP
IMP: Inferred from mutant phenotype
20430745 MGI
acts upstream of or within positive regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
20430745 MGI
involved in positive regulation of translation IDA
IDA: Inferred from direct assay
35951695 MGI
acts upstream of or within positive regulation of translation IMP
IMP: Inferred from mutant phenotype
20430745 MGI
involved in spermatid development IDA
IDA: Inferred from direct assay
35951695 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
20430745 MGI
acts upstream of translation IMP
IMP: Inferred from mutant phenotype
20430745 MGI
Cellular Component GO Annotation Evidence References Source
is active in intracellular non-membrane-bounded organelle IDA
IDA: Inferred from direct assay
35951695 MGI
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 4 gamma 3

  • eIF-4-gamma 3

  • eIF-4-gamma II

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04283 EIF4G3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif4g3 NCBI NCBI:8672