Samd11 - sterile alpha motif domain containing 11 Gene

Also Known as mr-s

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231004

Summary

Enables PH domain binding activity; SAM domain binding activity; and protein self-association. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in photoreceptor layer; pineal gland; retina; retina layer; and retina outer nuclear layer. Orthologous to human SAMD11 (sterile alpha motif domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]

Samd11 Products (2)

mRNA Protein Name
NM_001110516.2 NP_001103986.1 sterile alpha motif domain-containing protein 11 isoform 1
NM_001355709.1 NP_001342638.1 sterile alpha motif domain-containing protein 11 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
33603070 MGI
enables PH domain binding IDA
IDA: Inferred from direct assay
16539743 MGI
enables SAM domain binding IDA
IDA: Inferred from direct assay
16539743 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
16539743 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
33603070 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16539743 MGI
involved in retinal rod cell development IMP
IMP: Inferred from mutant phenotype
33603070 MGI
Cellular Component GO Annotation Evidence References Source
part of PRC1 complex IDA
IDA: Inferred from direct assay
33603070 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16539743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sterile alpha motif domain-containing protein 11

  • SAM domain-containing protein 11

  • major retinal SAM domain-containing protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12423 SAMD11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Samd11 NCBI NCBI:148398