2. Gene
  3. Gbx1 - gastrulation brain homeobox 1 Gene

Gbx1 - gastrulation brain homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gbx-1

Gene ID: 231044 | Gene type: protein coding

About Gbx1

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within adult walking behavior; neuron differentiation; and proprioception. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; embryo mesenchyme; extraembryonic component; and eye. Orthologous to human GBX1 (gastrulation brain homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Gbx1 Products(1)

mRNA Protein Name
NM_015739.2 NP_056554.1 homeobox protein GBX-1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within adult walking behavior IMP
IMP: Inferred from mutant phenotype
23418536 MGI
acts upstream of or within neuron fate commitment IMP
IMP: Inferred from mutant phenotype
24010020 MGI
acts upstream of or within proprioception IMP
IMP: Inferred from mutant phenotype
23418536 MGI
acts upstream of or within sensory neuron axon guidance IMP
IMP: Inferred from mutant phenotype
23418536 MGI
acts upstream of or within spinal cord motor neuron differentiation IMP
IMP: Inferred from mutant phenotype
23418536 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
24010020 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein GBX-1

gastrulation and brain-specific homeobox protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05314 GBX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gbx1 NCBI NCBI:2636