Polr2b - polymerase (RNA) II (DNA directed) polypeptide B Gene

Mus musculus

Also known as Rpb2; Pol2rb; Rpb140

Gene ID: 231329 | Gene type: protein coding

About Polr2b

Summary

Enables chromatin binding activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II, core complex. Predicted to colocalize with chromosome, telomeric region. Is expressed in several structures, including alimentary system; brain; integumental system; respiratory system; and sensory organ. Orthologous to human POLR2B (RNA polymerase II subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Polr2b Products(1)

mRNA	Protein	Name
NM_153798.2	NP_722493.2	DNA-directed RNA polymerase II subunit RPB2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IDA IDA: Inferred from direct assay	22287103	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

DNA-directed RNA polymerase II subunit RPB2

DNA-directed RNA polymerase II 140 kDa polypeptide	DNA-directed RNA polymerase II subunit B
RNA polymerase II subunit 2	RNA polymerase II subunit B2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10843	POLR2B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Polr2b	NCBI	NCBI:5431

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