Arhgap24 - Rho GTPase activating protein 24 Gene

Also Known as 0610025G21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231532

Summary

Enables GTPase activator activity. Acts upstream of or within several processes, including activation of GTPase activity; negative regulation of Rac protein signal transduction; and negative regulation of ruffle assembly. Located in focal adhesion. Is expressed in several structures, including axial skeleton; central nervous system; cranium; jaw; and metanephros. Orthologous to human ARHGAP24 (Rho GTPase activating protein 24). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap24 Products (4)

mRNA Protein Name
NM_001286468.1 NP_001273397.1 rho GTPase-activating protein 24 isoform 2
NM_001346585.1 NP_001333514.1 rho GTPase-activating protein 24 isoform 3
NM_029270.2 NP_083546.2 rho GTPase-activating protein 24 isoform 1
NM_146161.3 NP_666273.1 rho GTPase-activating protein 24 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IMP
IMP: Inferred from mutant phenotype
21911940 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of Rac protein signal transduction IMP
IMP: Inferred from mutant phenotype
21911940 MGI
acts upstream of or within activation of GTPase activity IMP
IMP: Inferred from mutant phenotype
21911940 MGI
acts upstream of or within negative regulation of Rac protein signal transduction IMP
IMP: Inferred from mutant phenotype
21911940 MGI
acts upstream of or within negative regulation of ruffle assembly IMP
IMP: Inferred from mutant phenotype
21911940 MGI
acts upstream of or within wound healing, spreading of epidermal cells IMP
IMP: Inferred from mutant phenotype
21911940 MGI
Cellular Component GO Annotation Evidence References Source
located in focal adhesion IDA
IDA: Inferred from direct assay
21911940 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 24

  • rho-type GTPase-activating protein 24

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00924 ARHGAP24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap24 NCBI NCBI:83478