2. Gene
  3. Arhgap24 - Rho GTPase activating protein 24 Gene

Arhgap24 - Rho GTPase activating protein 24 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 0610025G21Rik

Gene ID: 231532 | Gene type: protein coding

About Arhgap24

Summary

Enables GTPase activator activity. Acts upstream of or within several processes, including activation of GTPase activity; negative regulation of Rac protein signal transduction; and negative regulation of ruffle assembly. Located in focal adhesion. Is expressed in several structures, including axial skeleton; central nervous system; cranium; jaw; and metanephros. Orthologous to human ARHGAP24 (Rho GTPase activating protein 24). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap24 Products(4)

mRNA Protein Name
NM_001286468.1 NP_001273397.1 rho GTPase-activating protein 24 isoform 2
NM_001346585.1 NP_001333514.1 rho GTPase-activating protein 24 isoform 3
NM_029270.2 NP_083546.2 rho GTPase-activating protein 24 isoform 1
NM_146161.3 NP_666273.1 rho GTPase-activating protein 24 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTPase activator activity IMP
IMP: Inferred from mutant phenotype
21911940 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of Rac protein signal transduction IMP
IMP: Inferred from mutant phenotype
21911940 MGI
acts upstream of or within activation of GTPase activity IMP
IMP: Inferred from mutant phenotype
21911940 MGI
acts upstream of or within negative regulation of Rac protein signal transduction IMP
IMP: Inferred from mutant phenotype
21911940 MGI
acts upstream of or within negative regulation of ruffle assembly IMP
IMP: Inferred from mutant phenotype
21911940 MGI
acts upstream of or within wound healing, spreading of epidermal cells IMP
IMP: Inferred from mutant phenotype
21911940 MGI
Cellular Component GO Annotation Evidence Reference Source
located in focal adhesion IDA
IDA: Inferred from direct assay
21911940 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 24

rho-type GTPase-activating protein 24

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00924 ARHGAP24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap24 NCBI NCBI:83478