Slc26a1 - solute carrier family 26 (sulfate transporter), member 1 Gene

Mus musculus

Also known as Sat1

Gene ID: 231583 | Gene type: protein coding

About Slc26a1

Summary

Enables anion transmembrane transporter activity. Involved in chloride transport. Acts upstream of or within oxalate transport and sulfate transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; integumental system; liver; nose; and urinary system. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis. Orthologous to human SLC26A1 (solute carrier family 26 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc26a1 Products(3)

mRNA	Protein	Name
NM_001310691.1	NP_001297620.1	sulfate anion transporter 1 isoform 1
NM_001310692.1	NP_001297621.1	sulfate anion transporter 1 isoform 2
NM_174870.4	NP_777359.3	sulfate anion transporter 1 isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables chloride transmembrane transporter activity	IDA IDA: Inferred from direct assay	12217875	MGI
enables oxalate transmembrane transporter activity	IDA IDA: Inferred from direct assay	12217875	MGI
enables sulfate transmembrane transporter activity	IDA IDA: Inferred from direct assay	12217875	MGI
enables sulfate transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	20160351	MGI
enables sulfate:bicarbonate antiporter activity	IDA IDA: Inferred from direct assay	12590734	MGI
enables sulfate:bicarbonate antiporter activity	IMP IMP: Inferred from mutant phenotype	27210743	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within chloride transport	IDA IDA: Inferred from direct assay	12590734	MGI
involved in chloride transport	IDA IDA: Inferred from direct assay	12217875	MGI
acts upstream of or within oxalate transport	IDA IDA: Inferred from direct assay	12590734	MGI
involved in oxalate transport	IDA IDA: Inferred from direct assay	12217875	MGI
acts upstream of or within sulfate transmembrane transport	IDA IDA: Inferred from direct assay	12590734	MGI
involved in sulfate transmembrane transport	IDA IDA: Inferred from direct assay	12217875	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	20160351	MGI
is active in plasma membrane	IDA IDA: Inferred from direct assay	20160351	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	27210743	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sulfate anion transporter 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13134	SLC26A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc26a1	NCBI	NCBI:10861

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