Tmem119 - transmembrane protein 119 Gene

Also Known as obif

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231633

Summary

Involved in several processes, including endochondral ossification; negative regulation of bone resorption; and positive regulation of macromolecule metabolic process. Acts upstream of or within osteoblast differentiation. Located in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and skeleton. Orthologous to human TMEM119 (transmembrane protein 119). [provided by Alliance of Genome Resources, Apr 2022]

Tmem119 Products (1)

mRNA Protein Name
NM_146162.3 NP_666274.1 transmembrane protein 119 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21239498 MGI
Biological Process GO Annotation Evidence References Source
involved in endochondral ossification IMP
IMP: Inferred from mutant phenotype
22416756 MGI
involved in negative regulation of bone resorption IMP
IMP: Inferred from mutant phenotype
22416756 MGI
involved in negative regulation of myotube differentiation IDA
IDA: Inferred from direct assay
22579779 MGI
acts upstream of or within osteoblast differentiation IDA
IDA: Inferred from direct assay
21239498 MGI
acts upstream of or within osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
21239498 MGI
involved in positive regulation of bone development IMP
IMP: Inferred from mutant phenotype
26207632 MGI
involved in positive regulation of bone mineralization IMP
IMP: Inferred from mutant phenotype
20025746 MGI
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
22579779 MGI
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22416756 MGI
involved in positive regulation of osteoblast differentiation IDA
IDA: Inferred from direct assay
22579779 MGI
involved in positive regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
20025746 MGI
involved in positive regulation of osteoblast proliferation IDA
IDA: Inferred from direct assay
20025746 MGI
involved in positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
22579779 MGI
involved in spermatid differentiation IMP
IMP: Inferred from mutant phenotype
26207632 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
26207632 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
21239498 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
20025746 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 119

  • osteoblast induction factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14655 TMEM119 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21263 Tmem119 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27782 Tmem119 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem119 NCBI NCBI:338773