Mepce - methylphosphate capping enzyme Gene

Mus musculus

Also known as Bcdin3; D5Wsu46e

Gene ID: 231803 | Gene type: protein coding

About Mepce

Summary

Predicted to enable 7SK snRNA binding activity and RNA 5'-methyltransferase activity. Acts upstream of or within negative regulation of chromatin binding activity; negative regulation of transcription by RNA polymerase II; and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be located in nucleus. Predicted to be part of 7SK snRNP. Is expressed in several structures, including adrenal gland; alimentary system; brain; early conceptus; and genitourinary system. Orthologous to human MEPCE (methylphosphate capping enzyme). [provided by Alliance of Genome Resources, Apr 2022]

Mepce Products(1)

mRNA	Protein	Name
NM_144913.3	NP_659162.3	7SK snRNA methylphosphate capping enzyme

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of chromatin binding	IGI IGI: Inferred from genetic interaction	23154982	MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	23154982	MGI
acts upstream of or within positive regulation of G1/S transition of mitotic cell cycle	IMP IMP: Inferred from mutant phenotype	23154982	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

7SK snRNA methylphosphate capping enzyme

bin3, bicoid-interacting 3, homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08338	MEPCE Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mepce	NCBI	NCBI:56257

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