2. Gene
  3. MEPCE - methylphosphate capping enzyme Gene

MEPCE - methylphosphate capping enzyme Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BCDIN3

Gene ID: 56257 | Gene type: protein coding

About MEPCE

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,428,790-100,434,118 (from NCBI)

This gene has 7 transcripts (splice variants), 196 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 29.4), spleen (RPKM 17.1) and 25 other tissues.

Summary

Enables 7SK snRNA binding activity and RNA 5'-methyltransferase activity. Involved in RNA modification; positive regulation of protein localization to Cajal body; and positive regulation of snRNA transcription by RNA polymerase II. Located in nucleus. Part of 7SK snRNP. [provided by Alliance of Genome Resources, Apr 2022]

MEPCE Products(5)

mRNA Protein Name
NM_001194990.2 NP_001181919.1 7SK snRNA methylphosphate capping enzyme isoform B
NM_001194991.2 NP_001181920.1 7SK snRNA methylphosphate capping enzyme isoform B
NM_001194992.2 NP_001181921.1 7SK snRNA methylphosphate capping enzyme isoform B
NM_001363486.2 NP_001350415.1 7SK snRNA methylphosphate capping enzyme isoform B
NM_019606.6 NP_062552.2 7SK snRNA methylphosphate capping enzyme isoform A

MEPCE Protein Structure

Bin3

Bin3: Bicoid-interacting protein 3 (Bin3) (574 - 683)

  • 0
  • 200
  • 400
  • 600
  • 689 a.a.
Protein Preferred Names Protein Names

7SK snRNA methylphosphate capping enzyme

bicoid-interacting protein 3 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08338 MEPCE Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MEPCE MGD MGI:106477
Bos taurus MEPCE VGNC VGNC:106819
Canis familiaris MEPCE VGNC VGNC:43161
Rattus norvegicus MEPCE RGD RGD:1560550
Macaca mulatta MEPCE VGNC VGNC:74541
Felis catus MEPCE VGNC VGNC:63450