2. Gene
  3. Brat1 - BRCA1-associated ATM activator 1 Gene

Brat1 - BRCA1-associated ATM activator 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Baat1

Gene ID: 231841 | Gene type: protein coding

About Brat1

Summary

A similar gene in human encodes a Breast Cancer 1 (BRCA1) interacting protein that is involved in cell cycle checkpoint signaling. The similar human protein is localized to DNA double strand breaks caused by ionizing radiation, and regulates cellular DNA damage response through interactions with Ataxia Telangiectasia Mutated (ATM) and DNA-dependent Protein Kinase. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Brat1 Products(2)

mRNA Protein Name
NM_001276287.1 NP_001263216.1 BRCA1-associated ATM activator 1 isoform 3
NM_181066.3 NP_851411.1 BRCA1-associated ATM activator 1 isoform 2
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25631046 MGI
located in nucleus IDA
IDA: Inferred from direct assay
25631046 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BRCA1-associated ATM activator 1

BRCA1-associated protein required for ATM activation protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01592 BRAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brat1 NCBI NCBI:221927