Cyp26b1 - cytochrome P450, family 26, subfamily b, polypeptide 1 Gene

Also Known as CP26; P450RAI-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 232174

Summary

Predicted to enable oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; retinoic acid 4-hydroxylase activity; and retinoic acid binding activity. Involved in positive regulation of gene expression; positive regulation of tongue muscle cell differentiation; and tongue morphogenesis. Acts upstream of or within several processes, including cellular response to retinoic acid; male gamete generation; and skin development. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Orthologous to human CYP26B1 (Cytochrome P450 family 26 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp26b1 Products (2)

mRNA Protein Name
NM_001177713.1 NP_001171184.1 cytochrome P450 26B1
NM_175475.3 NP_780684.1 cytochrome P450 26B1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell fate determination IMP
IMP: Inferred from mutant phenotype
16574820 MGI
involved in cellular response to retinoic acid IEP
IEP: Inferred from expression pattern
18816858 MGI
acts upstream of or within cornification IMP
IMP: Inferred from mutant phenotype
22366455 MGI
acts upstream of or within embryonic limb morphogenesis IMP
IMP: Inferred from mutant phenotype
15030763 MGI
acts upstream of or within establishment of T cell polarity IMP
IMP: Inferred from mutant phenotype
23991089 MGI
acts upstream of or within establishment of skin barrier IMP
IMP: Inferred from mutant phenotype
22366455 MGI
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
23991089 MGI
acts upstream of or within male meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
16574820 MGI
acts upstream of or within negative regulation of retinoic acid receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
22366455 MGI
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
18816858 MGI
involved in positive regulation of tongue muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
18816858 MGI
acts upstream of or within proximal/distal pattern formation IMP
IMP: Inferred from mutant phenotype
15030763 MGI
acts upstream of or within regulation of T cell differentiation IMP
IMP: Inferred from mutant phenotype
23991089 MGI
acts upstream of or within regulation of retinoic acid receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
23991089 MGI
acts upstream of or within retinoic acid receptor signaling pathway IDA
IDA: Inferred from direct assay
15030763 MGI
acts upstream of retinoic acid receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
22366455 MGI
involved in retinoic acid receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
18816858 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
16574820 MGI
involved in tongue morphogenesis IMP
IMP: Inferred from mutant phenotype
18816858 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 26B1

  • cytochrome P450 retinoic acid-inactivating 2

  • cytochrome P450, 26, retinoic acid B1

  • cytochrome P450RAI-2

  • retinoic acid B1

  • retinoic acid hydroxylase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-14531 Talarozole Inhibitor 99.75% Phase 2

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-182728 CD564 Inhibitor / Unkown
HY-RS03448 CYP26B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp26b1 NCBI NCBI:56603