Tmf1 - TATA element modulatory factor 1 Gene

Also Known as Gm153; Tmf1`; 7030402D04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 232286

Summary

Predicted to enable Androgen Receptor binding activity and nuclear receptor coactivator activity. Involved in regulation of proteasomal protein catabolic process. Acts upstream of or within several processes, including Leydig cell differentiation; regulation of gene expression; and spermatid development. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in mandible and maxilla. Orthologous to human TMF1 (TATA element modulatory factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Tmf1 Products (1)

mRNA Protein Name
NM_001081111.2 NP_001074580.1 TATA element modulatory factor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16792503 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Leydig cell differentiation IMP
IMP: Inferred from mutant phenotype
23000399 MGI
acts upstream of or within acrosome assembly IMP
IMP: Inferred from mutant phenotype
20691678 MGI
acts upstream of apoptotic process IMP
IMP: Inferred from mutant phenotype
23000399 MGI
acts upstream of or within cellular response to organic cyclic compound IMP
IMP: Inferred from mutant phenotype
22531781 MGI
acts upstream of or within defense response to bacterium IMP
IMP: Inferred from mutant phenotype
22553199 MGI
acts upstream of epithelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
23000399 MGI
acts upstream of or within flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
20691678 MGI
acts upstream of or within luteinizing hormone secretion IMP
IMP: Inferred from mutant phenotype
23000399 MGI
acts upstream of or within male gonad development IMP
IMP: Inferred from mutant phenotype
20691678 MGI
acts upstream of or within negative regulation of epithelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
23000399 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22553199 MGI
acts upstream of or within positive regulation of cytokine production IMP
IMP: Inferred from mutant phenotype
22553199 MGI
acts upstream of or within positive regulation of testosterone secretion IMP
IMP: Inferred from mutant phenotype
23000399 MGI
involved in regulation of proteasomal protein catabolic process IDA
IDA: Inferred from direct assay
16792503 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
20691678 MGI
acts upstream of or within spermatid nucleus differentiation IMP
IMP: Inferred from mutant phenotype
20691678 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
20691678 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
23000399 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TATA element modulatory factor

  • TMF

  • androgen receptor coactivator 160 kDa protein

  • androgen receptor-associated protein of 160 kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14754 TMF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmf1 NCBI NCBI:7110