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TMF1 - TATA element modulatory factor 1 Gene

Also Known as TMF; ARA160

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7110

About TMF1

Cytogenetic location: 3p14.1 Genomic coordinates (GRCh38): 3:69,019,827-69,052,333 (from NCBI)

This gene has 7 transcripts (splice variants), 205 orthologues and 43 paralogues. Ubiquitous expression in testis (RPKM 20.2), thyroid (RPKM 13.7) and 25 other tissues.

Summary

Enables Androgen Receptor binding activity and nuclear receptor coactivator activity. Involved in Androgen Receptor signaling pathway and positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

TMF1 Products (2)

mRNA	Protein	Name
NM_001363879.1	NP_001350808.1	TATA element modulatory factor isoform 2
NM_007114.3	NP_009045.2	TATA element modulatory factor isoform 1

TMF1 Protein Structure

TMF_DNA_bd

TMF_TATA_bd

0
200
400
600
800
1000
1093 a.a.

Protein Preferred Names	Protein Names
TATA element modulatory factor	androgen receptor coactivator 160 kDa protein

TMF1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	TMF1	P82094	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Prey Pooling	32296183
Intra	TMF1	P82094	CMTM5	Homo sapiens	Q96DZ9-2	Validated Y2H	32296183
Intra	TMF1	P82094	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Array	32296183
Intra	TMF1	P82094	NR3C1	Homo sapiens	P04150	Display Tech	20195357
Intra	TMF1	P82094	NR3C1	Homo sapiens	P04150	TAP	20195357

Cross: Cross-species interaction Intra: Intraspecies interaction

TMF1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P87110	TMF Antibody (YA6803)	WB, ICC/IF, IHC-P	Human

Related Diseases

Diseases	Alias
Achondrogenesis, Type Ia	Achondrogenesis Type Ia Achondrogenesis Type 1a ACG1A Achondrogenesis, Houston-Harris Type Achondrogenesis Houston-Harris Type Achondrogenesis 1a Acg-Ia
Corneal Dystrophy, Gelatinous Drop-Like	Gelatinous Drop-Like Corneal Dystrophy GDLD Cdgdl Corneal Amyloidosis Lattice Corneal Dystrophy Type Iii Amyloidosis, Corneal Amyloid Corneal Dystrophy, Japanese Type Gdcd Primary Familial Amyloidosis Of The Cornea Subepithelial Amyloidosis Of The Cornea Corneal Dystrophy, Lattice Type 3 Corneal Dystrophy, Lattice Type Iii Lattice Corneal Dystrophy, Type Iii Amyloidosis Corneal Lattice Corneal Dystrophy Type3 Amyloid Corneal Dystrophy Japanese Type Dystrophy, Corneal, Gelatinous Drop-Like Amyloid Of Cornea

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14754	TMF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TMF1	MGD	MGI:2684999
Bos taurus	TMF1	VGNC	VGNC:36132
Rattus norvegicus	TMF1	RGD	RGD:620551
Canis familiaris	TMF1	VGNC	VGNC:47620
Macaca mulatta	TMF1	VGNC	VGNC:82710
Felis catus	TMF1	VGNC	VGNC:66375
Others	TMF1	NCBI