TMF1 - TATA element modulatory factor 1 Gene

Homo sapiens

Also known as TMF; ARA160

Gene ID: 7110 | Gene type: protein coding

About TMF1

Cytogenetic location: 3p14.1 Genomic coordinates (GRCh38): 3:69,019,827-69,052,333 (from NCBI)

This gene has 7 transcripts (splice variants), 205 orthologues and 43 paralogues. Ubiquitous expression in testis (RPKM 20.2), thyroid (RPKM 13.7) and 25 other tissues.

Summary

Enables Androgen Receptor binding activity and nuclear receptor coactivator activity. Involved in Androgen Receptor signaling pathway and positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

TMF1 Products(2)

mRNA	Protein	Name
NM_001363879.1	NP_001350808.1	TATA element modulatory factor isoform 2
NM_007114.3	NP_009045.2	TATA element modulatory factor isoform 1

TMF1 Protein Structure

TMF_DNA_bd

TMF_TATA_bd

0
200
400
600
800
1000
1093 a.a.

Protein Preferred Names

Protein Names

TATA element modulatory factor

androgen receptor coactivator 160 kDa protein

Related Diseases

Diseases

Alias

Achondrogenesis, Type Ia

Achondrogenesis Type Ia	Achondrogenesis Type 1a
ACG1A	Achondrogenesis, Houston-Harris Type
Achondrogenesis Houston-Harris Type	Achondrogenesis 1a
Acg-Ia

Corneal Dystrophy, Gelatinous Drop-Like

Gelatinous Drop-Like Corneal Dystrophy	GDLD
Cdgdl	Corneal Amyloidosis
Lattice Corneal Dystrophy Type Iii	Amyloidosis, Corneal
Amyloid Corneal Dystrophy, Japanese Type	Gdcd
Primary Familial Amyloidosis Of The Cornea	Subepithelial Amyloidosis Of The Cornea
Corneal Dystrophy, Lattice Type 3	Corneal Dystrophy, Lattice Type Iii
Lattice Corneal Dystrophy, Type Iii	Amyloidosis Corneal
Lattice Corneal Dystrophy Type3	Amyloid Corneal Dystrophy Japanese Type
Dystrophy, Corneal, Gelatinous Drop-Like	Amyloid Of Cornea

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14754	TMF1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TMF1	MGD	MGI:2684999
Bos taurus	TMF1	VGNC	VGNC:36132
Rattus norvegicus	TMF1	RGD	RGD:620551
Canis familiaris	TMF1	VGNC	VGNC:47620
Macaca mulatta	TMF1	VGNC	VGNC:82710
Felis catus	TMF1	VGNC	VGNC:66375

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