2. Gene
  3. Ap2s1 - adaptor-related protein complex 2, sigma 1 subunit Gene

Ap2s1 - adaptor-related protein complex 2, sigma 1 subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 232910 | Gene type: protein coding

About Ap2s1

Summary

Predicted to enable clathrin adaptor activity. Predicted to be involved in vesicle-mediated transport. Predicted to act upstream of or within endocytosis. Part of AP-2 adaptor complex. Human ortholog(s) of this gene implicated in familial hypocalciuric hypercalcemia 3. Orthologous to human AP2S1 (adaptor related protein complex 2 subunit sigma 1). [provided by Alliance of Genome Resources, Apr 2022]

Ap2s1 Products(1)

mRNA Protein Name
NM_198613.2 NP_941015.2 AP-2 complex subunit sigma
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12086608 MGI
Cellular Component GO Annotation Evidence Reference Source
part of AP-2 adaptor complex IDA
IDA: Inferred from direct assay
12086608 MGI
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AP-2 complex subunit sigma

adapter-related protein complex 2 sigma subunit

adapter-related protein complex 2 subunit sigma

adaptor protein complex AP-2 subunit sigma

adaptor-related protein complex 2 subunit sigma

clathrin assembly protein 2 sigma small chain

clathrin assembly

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00788 AP2S1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ap2s1 NCBI NCBI:1175