Rasgrp4 - RAS guanyl releasing protein 4 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 233046

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in cell population proliferation; positive regulation of Ras protein signal transduction; and response to extracellular stimulus. Predicted to act upstream of or within cell differentiation. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Is expressed in several structures, including genitourinary system; liver; peritoneal cavity; spleen; and tongue. Orthologous to human RASGRP4 (Ras guanyl releasing protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Rasgrp4 Products (2)

mRNA Protein Name
NM_001174155.1 NP_001167626.1 RAS guanyl-releasing protein 4 isoform 1
NM_145149.4 NP_660131.2 RAS guanyl-releasing protein 4 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables diacylglycerol binding IDA
IDA: Inferred from direct assay
17523924 MGI
Biological Process GO Annotation Evidence References Source
involved in antibacterial innate immune response IMP
IMP: Inferred from mutant phenotype
26982501 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
22728827 MGI
involved in positive regulation of natural killer cell mediated immunity IMP
IMP: Inferred from mutant phenotype
26982501 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
11956218 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RAS guanyl-releasing protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11696 RASGRP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rasgrp4 NCBI NCBI:115727