Lim2 - lens intrinsic membrane protein 2 Gene

Also Known as To3; MP17; MP18; MP19; MP20; 4833403J20

Species: Mus musculus

Gene Type: protein coding
Gene ID: 233187

Summary

Predicted to be a structural constituent of eye lens. Acts upstream of or within lens development in camera-type eye. Predicted to be located in vesicle. Predicted to be active in plasma membrane. Is expressed in embryo; head; inter-parietal bone primordium; and lens. Used to study cataract and cataract 19 multiple types. Human ortholog(s) of this gene implicated in cataract and cataract 19 multiple types. Orthologous to several human genes including LIM2 (lens intrinsic membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Lim2 Products (1)

mRNA Protein Name
NM_177693.4 NP_808361.1 lens fiber membrane intrinsic protein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within camera-type eye development IMP
IMP: Inferred from mutant phenotype
9238094 MGI
acts upstream of or within lens development in camera-type eye IMP
IMP: Inferred from mutant phenotype
6510713 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lens fiber membrane intrinsic protein

  • total opacity 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07656 LIM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07669 LIMS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20764 Lhx5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21366 Lhx2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lim2 NCBI NCBI:3982