2. Gene
  3. Spon1 - spondin 1, (f-spondin) extracellular matrix protein Gene

Spon1 - spondin 1, (f-spondin) extracellular matrix protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FSP; D330035F22Rik

Gene ID: 233744 | Gene type: protein coding

About Spon1

Summary

Enables LBD domain binding activity. Acts upstream of or within positive regulation of protein binding activity; positive regulation of protein processing; and regulation of amyloid precursor protein catabolic process. Located in collagen-containing extracellular matrix. Is expressed in aorta; jaw bone; nervous system; and sensory organ. Orthologous to human SPON1 (spondin 1). [provided by Alliance of Genome Resources, Apr 2022]

Spon1 Products(1)

mRNA Protein Name
NM_145584.2 NP_663559.1 spondin-1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables LBD domain binding IPI
IPI: Inferred from physical interaction
16227578 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16227578 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of amyloid-beta formation IDA
IDA: Inferred from direct assay
16227578 MGI
acts upstream of or within positive regulation of amyloid precursor protein catabolic process IDA
IDA: Inferred from direct assay
16227578 MGI
acts upstream of or within positive regulation of protein binding IDA
IDA: Inferred from direct assay
16227578 MGI
acts upstream of or within positive regulation of protein processing IDA
IDA: Inferred from direct assay
16227578 MGI
acts upstream of protein processing IDA
IDA: Inferred from direct assay
16227578 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spondin-1

F-spondin

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13698 SPON1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spon1 NCBI NCBI:10418