Tnrc6a - trinucleotide repeat containing 6a Gene

Also Known as GW182; Tnrc6; CAGH26; 2010321I05Rik; 3110054G10Rik; D130023A07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 233833

Summary

This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein is highly similar to a human protein that functions in post-transcriptional gene silencing through the RNA interference (RNAi) and MicroRNA pathways. The human protein associates with messenger RNAs and argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies, and inhibiting its expression delocalizes Other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]

Tnrc6a Products (1)

mRNA Protein Name
NM_144925.3 NP_659174.3 trinucleotide repeat-containing gene 6A protein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to starvation IDA
IDA: Inferred from direct assay
15494374 MGI
acts upstream of or within endoderm development IMP
IMP: Inferred from mutant phenotype
28811219 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trinucleotide repeat-containing gene 6A protein

  • GW182 autoantigen

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14864 TNRC6A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnrc6a NCBI NCBI:27327