Pcid2 - PCI domain containing 2 Gene

Mus musculus

Also known as A730042J05Rik

Gene ID: 234069 | Gene type: protein coding

About Pcid2

Summary

Predicted to enable RNA binding activity and double-stranded DNA binding activity. Involved in several processes, including positive regulation of B cell differentiation; positive regulation of mitotic cell cycle spindle assembly checkpoint; and spleen development. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nuclear pore nuclear basket and transcription export complex 2. Is expressed in lung; nervous system; retina layer; and skeletal muscle. Orthologous to human PCID2 (PCI domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Pcid2 Products(1)

mRNA	Protein	Name
NM_178708.3	NP_848823.2	PCI domain-containing protein 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	29138493	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in heterochromatin organization	IMP IMP: Inferred from mutant phenotype	29138493	MGI
involved in negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	20870947	MGI
involved in negative regulation of lymphoid progenitor cell differentiation	IMP IMP: Inferred from mutant phenotype	29138493	MGI
involved in negative regulation of transcription initiation by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	29138493	MGI
involved in positive regulation of B cell differentiation	IMP IMP: Inferred from mutant phenotype	20870947	MGI
involved in positive regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	20870947	MGI
involved in positive regulation of mitotic cell cycle spindle assembly checkpoint	IMP IMP: Inferred from mutant phenotype	20870947	MGI
involved in spleen development	IMP IMP: Inferred from mutant phenotype	20870947	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

PCI domain-containing protein 2

CSN12-like protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10150	PCID2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pcid2	NCBI	NCBI:55795

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