2. Gene
  3. Tmem231 - transmembrane protein 231 Gene

Tmem231 - transmembrane protein 231 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm178; 4932417I16Rik

Gene ID: 234740 | Gene type: protein coding

About Tmem231

Summary

Acts upstream of or within several processes, including embryonic digit morphogenesis; neuroepithelial cell differentiation; and smoothened signaling pathway. Located in ciliary membrane and ciliary transition zone. Part of MKS complex. Is expressed in embryo. Human ortholog(s) of this gene implicated in Joubert syndrome 20 and Meckel syndrome. Orthologous to human TMEM231 (transmembrane protein 231). [provided by Alliance of Genome Resources, Apr 2022]

Tmem231 Products(2)

mRNA Protein Name
NM_001033321.2 NP_001028493.1 transmembrane protein 231 isoform 1
NM_001357348.1 NP_001344277.1 transmembrane protein 231 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22179047 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within camera-type eye development IMP
IMP: Inferred from mutant phenotype
22179047 MGI
acts upstream of or within cilium assembly IMP
IMP: Inferred from mutant phenotype
22179047 MGI
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
22179047 MGI
acts upstream of or within embryonic digit morphogenesis IMP
IMP: Inferred from mutant phenotype
22179047 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
22179047 MGI
acts upstream of or within neuroepithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
22179047 MGI
acts upstream of or within regulation of protein localization IMP
IMP: Inferred from mutant phenotype
22179047 MGI
acts upstream of or within smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
22179047 MGI
involved in smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
22179047 MGI
acts upstream of or within vasculature development IMP
IMP: Inferred from mutant phenotype
22179047 MGI
Cellular Component GO Annotation Evidence Reference Source
part of MKS complex IDA
IDA: Inferred from direct assay
22179047 MGI
located in ciliary membrane IDA
IDA: Inferred from direct assay
22179047 MGI
located in ciliary transition zone IDA
IDA: Inferred from direct assay
22179047 MGI
located in membrane IDA
IDA: Inferred from direct assay
22179047 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 231

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14703 TMEM231 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem231 NCBI NCBI:79583