Septin7 - septin 7 Gene

Mus musculus

Also known as Cdc10; Sept7; E430034N22

Gene ID: 235072 | Gene type: protein coding

About Septin7

Summary

Predicted to enable GTPase activity; identical protein binding activity; and molecular adaptor activity. Acts upstream of or within cortical Cytoskeleton organization; mitotic cytokinesis; and plasma membrane bounded cell projection organization. Located in axon terminus; cell body; and septin Cytoskeleton. Part of septin complex. Is active in presynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SEPTIN7 (septin 7). [provided by Alliance of Genome Resources, Apr 2022]

Septin7 Products(5)

mRNA	Protein	Name
NM_001205367.2	NP_001192296.1	septin-7 isoform 2
NM_001359736.1	NP_001346665.1	septin-7 isoform 3
NM_001359737.2	NP_001346666.1	septin-7 isoform 3
NM_001359738.1	NP_001346667.1	septin-7 isoform 3
NM_009859.4	NP_033989.2	septin-7 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11739749	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within D-glucose import	IMP IMP: Inferred from mutant phenotype	22809625	MGI
acts upstream of or within collateral sprouting	IMP IMP: Inferred from mutant phenotype	24113571	MGI
acts upstream of or within cortical cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	22232702	MGI
acts upstream of or within dendritic spine morphogenesis	IMP IMP: Inferred from mutant phenotype	24113571	MGI
acts upstream of or within mitotic cytokinesis	IMP IMP: Inferred from mutant phenotype	25122120	MGI
acts upstream of or within pseudopodium retraction	IMP IMP: Inferred from mutant phenotype	22232702	MGI
acts upstream of or within regulation of protein binding	IMP IMP: Inferred from mutant phenotype	22809625	MGI
acts upstream of or within vesicle-mediated transport	IMP IMP: Inferred from mutant phenotype	22809625	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in axon terminus	IDA IDA: Inferred from direct assay	11064363	MGI
located in cell cortex	IDA IDA: Inferred from direct assay	11064363	MGI
is active in cytoplasm	IDA IDA: Inferred from direct assay	22809625	MGI
is active in membrane	IDA IDA: Inferred from direct assay	22809625	MGI
located in neuron projection	IDA IDA: Inferred from direct assay	24113571	MGI
located in neuronal cell body	IDA IDA: Inferred from direct assay	24113571	MGI
is active in plasma membrane	IDA IDA: Inferred from direct assay	22809625	MGI
is active in presynaptic membrane	IDA IDA: Inferred from direct assay	11064363	MGI
part of protein-containing complex	IDA IDA: Inferred from direct assay	22508986	MGI
part of septin complex	IDA IDA: Inferred from direct assay	18809578	MGI
part of septin complex	IMP IMP: Inferred from mutant phenotype	22232702	MGI
located in septin cytoskeleton	IDA IDA: Inferred from direct assay	22508986	MGI
located in septin filament array	IDA IDA: Inferred from direct assay	22232702	MGI
located in septin ring	IDA IDA: Inferred from direct assay	22232702	MGI
located in synapse	IDA IDA: Inferred from direct assay	11739749	MGI
is active in vesicle	IDA IDA: Inferred from direct assay	22809625	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

septin-7

CDC10 protein homolog

cell division cycle 10 homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12684	SEPTIN7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Septin7	NCBI	NCBI:989

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