Septin7 - septin 7 Gene

Also Known as Cdc10; Sept7; E430034N22

Species: Mus musculus

Gene Type: protein coding
Gene ID: 235072

Summary

Predicted to enable GTPase activity; identical protein binding activity; and molecular adaptor activity. Acts upstream of or within cortical Cytoskeleton organization; mitotic cytokinesis; and plasma membrane bounded cell projection organization. Located in axon terminus; cell body; and septin Cytoskeleton. Part of septin complex. Is active in presynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SEPTIN7 (septin 7). [provided by Alliance of Genome Resources, Apr 2022]

Septin7 Products (5)

mRNA Protein Name
NM_001205367.2 NP_001192296.1 septin-7 isoform 2
NM_001359736.1 NP_001346665.1 septin-7 isoform 3
NM_001359737.2 NP_001346666.1 septin-7 isoform 3
NM_001359738.1 NP_001346667.1 septin-7 isoform 3
NM_009859.4 NP_033989.2 septin-7 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11739749 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within D-glucose import IMP
IMP: Inferred from mutant phenotype
22809625 MGI
acts upstream of or within collateral sprouting IMP
IMP: Inferred from mutant phenotype
24113571 MGI
acts upstream of or within cortical cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
22232702 MGI
acts upstream of or within dendritic spine morphogenesis IMP
IMP: Inferred from mutant phenotype
24113571 MGI
acts upstream of or within mitotic cytokinesis IMP
IMP: Inferred from mutant phenotype
25122120 MGI
acts upstream of or within pseudopodium retraction IMP
IMP: Inferred from mutant phenotype
22232702 MGI
acts upstream of or within regulation of protein binding IMP
IMP: Inferred from mutant phenotype
22809625 MGI
acts upstream of or within vesicle-mediated transport IMP
IMP: Inferred from mutant phenotype
22809625 MGI
Cellular Component GO Annotation Evidence References Source
located in axon terminus IDA
IDA: Inferred from direct assay
11064363 MGI
located in cell cortex IDA
IDA: Inferred from direct assay
11064363 MGI
is active in cytoplasm IDA
IDA: Inferred from direct assay
22809625 MGI
is active in membrane IDA
IDA: Inferred from direct assay
22809625 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
24113571 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
24113571 MGI
is active in plasma membrane IDA
IDA: Inferred from direct assay
22809625 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
11064363 MGI
part of protein-containing complex IDA
IDA: Inferred from direct assay
22508986 MGI
part of septin complex IDA
IDA: Inferred from direct assay
18809578 MGI
part of septin complex IMP
IMP: Inferred from mutant phenotype
22232702 MGI
located in septin cytoskeleton IDA
IDA: Inferred from direct assay
22508986 MGI
located in septin filament array IDA
IDA: Inferred from direct assay
22232702 MGI
located in septin ring IDA
IDA: Inferred from direct assay
22232702 MGI
located in synapse IDA
IDA: Inferred from direct assay
11739749 MGI
is active in vesicle IDA
IDA: Inferred from direct assay
22809625 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

septin-7

  • CDC10 protein homolog

  • cell division cycle 10 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12684 SEPTIN7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Septin7 NCBI NCBI:989