Spry3 - sprouty RTK signaling antagonist 3 Gene

Also Known as Gm391; Gm1409; sprouty3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 236576

Summary

Involved in negative regulation of ERK1 and ERK2 cascade and negative regulation of neuron projection arborization. Predicted to be located in cytoplasm and membrane. Is expressed in brain; head; pancreas; and testis. Orthologous to human SPRY3 (sprouty RTK signaling antagonist 3). [provided by Alliance of Genome Resources, Apr 2022]

Spry3 Products (4)

mRNA Protein Name
NM_001030293.3 NP_001025464.1 protein sprouty homolog 3
NM_001401849.1 NP_001388778.1 protein sprouty homolog 3
NM_001401850.1 NP_001388779.1 protein sprouty homolog 3
NM_001401851.1 NP_001388780.1 protein sprouty homolog 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16339969 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
16877379 MGI
involved in negative regulation of neuron projection arborization IMP
IMP: Inferred from mutant phenotype
26089202 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein sprouty homolog 3

  • sprouty homolog 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13723 SPRY3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spry3 NCBI NCBI:10251