2. Gene
  3. Spry3 - sprouty RTK signaling antagonist 3 Gene

Spry3 - sprouty RTK signaling antagonist 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm391; Gm1409; sprouty3

Gene ID: 236576 | Gene type: protein coding

About Spry3

Summary

Involved in negative regulation of ERK1 and ERK2 cascade and negative regulation of neuron projection arborization. Predicted to be located in cytoplasm and membrane. Is expressed in brain; head; pancreas; and testis. Orthologous to human SPRY3 (sprouty RTK signaling antagonist 3). [provided by Alliance of Genome Resources, Apr 2022]

Spry3 Products(4)

mRNA Protein Name
NM_001030293.3 NP_001025464.1 protein sprouty homolog 3
NM_001401849.1 NP_001388778.1 protein sprouty homolog 3
NM_001401850.1 NP_001388779.1 protein sprouty homolog 3
NM_001401851.1 NP_001388780.1 protein sprouty homolog 3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16339969 MGI
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
16877379 MGI
involved in negative regulation of neuron projection arborization IMP
IMP: Inferred from mutant phenotype
26089202 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein sprouty homolog 3

sprouty homolog 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13723 SPRY3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spry3 NCBI NCBI:10251