Glra2 - glycine receptor, alpha 2 subunit Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 237213

Summary

Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in several processes, including cellular response to ethanol; cellular response to zinc ion; and chloride transmembrane transport. Located in glycinergic synapse. Is expressed in brain and spinal cord. Orthologous to human GLRA2 (glycine receptor alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Glra2 Products (3)

mRNA Protein Name
NM_001357099.1 NP_001344028.1 glycine receptor subunit alpha-2 isoform a precursor
NM_001357100.1 NP_001344029.1 glycine receptor subunit alpha-2 isoform b precursor
NM_183427.5 NP_906272.1 glycine receptor subunit alpha-2 isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
19528249 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
19528249 MGI
Biological Process GO Annotation Evidence References Source
involved in modulation of chemical synaptic transmission EXP
EXP: Inferred from Experiment
30374290 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
30374290 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
30374290 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
15329889 MGI
is active in glycinergic synapse IDA
IDA: Inferred from direct assay
19528249 MGI
is active in glycinergic synapse IMP
IMP: Inferred from mutant phenotype
19528249 MGI
is active in postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
15329889 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycine receptor subunit alpha-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05493 GLRA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glra2 NCBI NCBI:2742