2. Gene
  3. Ric8b - RIC8 guanine nucleotide exchange factor B Gene

Ric8b - RIC8 guanine nucleotide exchange factor B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ric-8; Ric-8b

Gene ID: 237422 | Gene type: protein coding

About Ric8b

Summary

Predicted to enable G-protein alpha-subunit binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in cytosol. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and immune system. Orthologous to human RIC8B (RIC8 guanine nucleotide exchange factor B). [provided by Alliance of Genome Resources, Apr 2022]

Ric8b Products(2)

mRNA Protein Name
NM_001013441.2 NP_001013459.1 synembryn-B isoform 1
NM_183172.2 NP_898995.1 synembryn-B isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables G-protein alpha-subunit binding IDA
IDA: Inferred from direct assay
16754875 MGI
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
16754875 MGI
enables protein folding chaperone IDA
IDA: Inferred from direct assay
22114146 MGI
Biological Process GO Annotation Evidence Reference Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
16754875 MGI
involved in sensory perception of smell IDA
IDA: Inferred from direct assay
29118104 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
22114146 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synembryn-B

resistance to inhibitors of cholinesterase 8 homolog B

resistance to inhibitors of cholinesterase 8B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11968 RIC8B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ric8b NCBI NCBI:55188