Coro1c - coronin, actin binding protein 1C Gene

Mus musculus

Also known as CRN2

Gene ID: 23790 | Gene type: protein coding

About Coro1c

Summary

Enables small GTPase binding activity. Involved in several processes, including activation of GTPase activity; regulation of fibroblast migration; and regulation of ruffle assembly. Located in Cytoskeleton. Part of flotillin complex. Is expressed in several structures, including brain; dorsal root ganglion; genitourinary system; liver; and spleen. Orthologous to human CORO1C (coronin 1C). [provided by Alliance of Genome Resources, Apr 2022]

Coro1c Products(1)

mRNA	Protein	Name
NM_011779.3	NP_035909.2	coronin-1C

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables small GTPase binding	IPI IPI: Inferred from physical interaction	25074804	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in activation of GTPase activity	IGI IGI: Inferred from genetic interaction	25074804	MGI
involved in activation of GTPase activity	IMP IMP: Inferred from mutant phenotype	25074804	MGI
acts upstream of or within corpus callosum development	IMP IMP: Inferred from mutant phenotype	29078390	MGI
involved in establishment of protein localization	IGI IGI: Inferred from genetic interaction	25074804	MGI
involved in establishment of protein localization	IMP IMP: Inferred from mutant phenotype	25074804	MGI
involved in regulation of fibroblast migration	IMP IMP: Inferred from mutant phenotype	25074804	MGI
involved in regulation of ruffle assembly	IGI IGI: Inferred from genetic interaction	25074804	MGI
acts upstream of or within ventricular system development	IMP IMP: Inferred from mutant phenotype	29078390	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoskeleton	IDA IDA: Inferred from direct assay	25074804	MGI
part of flotillin complex	IDA IDA: Inferred from direct assay	25074804	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

coronin-1C

coronin 1c

coronin-3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03050	CORO1C Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Coro1c	NCBI	NCBI:23603

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