Enpp7 - ectonucleotide pyrophosphatase/phosphodiesterase 7 Gene

Also Known as Gm254; NPP-7; E-NPP 7; Alk-SMase

Species: Mus musculus

Gene Type: protein coding
Gene ID: 238011

Summary

Enables sphingomyelin phosphodiesterase activity. Involved in several processes, including fatty acid homeostasis; positive regulation of intestinal Cholesterol absorption; and regulation of membrane lipid metabolic process. Predicted to be located in Golgi apparatus and microvillus. Predicted to be integral component of plasma membrane. Orthologous to human ENPP7 (ectonucleotide pyrophosphatase/phosphodiesterase 7). [provided by Alliance of Genome Resources, Apr 2022]

Enpp7 Products (1)

mRNA Protein Name
NM_001359574.1 NP_001346503.1 ectonucleotide pyrophosphatase/phosphodiesterase family member 7 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Referencias Source
enables sphingomyelin phosphodiesterase activity IMP
IMP: Inferred from mutant phenotype
21177474 MGI
Biological Process GO Annotation Evidence Referencias Source
involved in fatty acid homeostasis IMP
IMP: Inferred from mutant phenotype
21177474 MGI
involved in lipid digestion IMP
IMP: Inferred from mutant phenotype
21177474 MGI
involved in positive regulation of ceramide biosynthetic process IMP
IMP: Inferred from mutant phenotype
21177474 MGI
involved in positive regulation of intestinal cholesterol absorption IMP
IMP: Inferred from mutant phenotype
24650549 MGI
involved in positive regulation of sphingomyelin catabolic process IMP
IMP: Inferred from mutant phenotype
21177474 MGI
involved in regulation of intestinal lipid absorption IMP
IMP: Inferred from mutant phenotype
21177474 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ectonucleotide pyrophosphatase/phosphodiesterase family member 7

  • alkaline sphingomyelin phosphodiesterase

  • intestinal alkaline sphingomyelinase

Recombinant Enpp7 Proteins

Referencia número Nombre del producto Accession Pureza
HY-P76902 ENPP-7 Protein, Mouse (HEK293, His) Q3TIW9 (A22-Q421) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS04393 ENPP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Enpp7 NCBI NCBI:339221