Lrfn5 - leucine rich repeat and fibronectin type III domain containing 5 Gene

Also Known as Salm5; mKIAA4208; C130061B21

Species: Mus musculus

Gene Type: protein coding
Gene ID: 238205

Summary

Involved in negative regulation of macrophage activation and regulation of presynapse assembly. Located in cell surface. Is active in GABA-ergic synapse and glutamatergic synapse. Is expressed in several structures, including central nervous system; dorsal root ganglion; and retina. Orthologous to human LRFN5 (leucine rich repeat and fibronectin type III domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Lrfn5 Products (2)

mRNA Protein Name
NM_001310586.1 NP_001297515.1 leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 2 precursor
NM_178714.5 NP_848829.2 leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27152329 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of macrophage activation IMP
IMP: Inferred from mutant phenotype
27152329 MGI
involved in regulation of presynapse assembly IDA
IDA: Inferred from direct assay
20410109 MGI
involved in regulation of presynapse assembly IMP
IMP: Inferred from mutant phenotype
20410109 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
20410109 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
20410109 MGI
located in cell surface IDA
IDA: Inferred from direct assay
16828986 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20410109 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
20410109 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat and fibronectin type-III domain-containing protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07783 LRFN5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21633 Lrfn5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28151 Lrfn5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrfn5 NCBI NCBI:145581