LRFN5 - leucine rich repeat and fibronectin type III domain containing 5 Gene

Homo sapiens

Also known as SALM5; FIGLER8; C14orf146

Gene ID: 145581 | Gene type: protein coding

About LRFN5

Cytogenetic location: 14q21.1 Genomic coordinates (GRCh38): 14:41,606,876-41,904,549 (from NCBI)

This gene has 5 transcripts (splice variants), 207 orthologues and 25 paralogues. Biased expression in brain (RPKM 2.4), adrenal (RPKM 0.8) and 13 other tissues.

Summary

This gene encodes a protein that belongs to the leucine-rich repeat and fibronectin type III domain-containing family of proteins. A similar protein in mouse, a glycosylated transmembrane protein, is thought to function in presynaptic differentiation. [provided by RefSeq, Sep 2016]

LRFN5 Products(4)

mRNA	Protein	Name
NM_001330106.2	NP_001317035.1	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 2 precursor
NM_001346173.2	NP_001333102.1	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 1 precursor
NM_001346175.2	NP_001333104.1	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 2 precursor
NM_152447.5	NP_689660.2	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 1 precursor

LRFN5 Protein Structure

LRR_5

I-set

0
200
400
600
719 a.a.

Protein Preferred Names

Protein Names

leucine-rich repeat and fibronectin type-III domain-containing protein 5

fibronectin type III, immunoglobulin and leucine rich repeat domains 8

Recombinant LRFN5 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P79386	LRFN5 Protein, Human (HEK293, hFc)	Q96NI6 (Q18-G527)	≥95%

Related Diseases

Diseases

Alias

Autism Spectrum Disorder

Asd	Autism Spectrum Disorders
Autistic Continuum	Pervasive Developmental Disorder
Pervasive Development Disorder	Autistic Behavior
Autistic Disorder	Autistic
Autistic Disorder Of Childhood Onset	Infantile Autism
Childhood Autism	Kanner Syndrome
Pervasive Developmental Delay Nos	Pervasive Developmental Disorder, Not Otherwise Specified

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07783	LRFN5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	LRFN5	VGNC	VGNC:42764
Macaca mulatta	LRFN5	VGNC	VGNC:74318
Mus musculus	LRFN5	MGD	MGI:2144814
Bos taurus	LRFN5	VGNC	VGNC:30979
Rattus norvegicus	LRFN5	RGD	RGD:1309357
Felis catus	LRFN5	VGNC	VGNC:63278

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